Chlorella Virus PBCV-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylases
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چکیده
Chlorella Virus PBCV-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylases. Rahul Shah, Catherine S. Coleman, Kiran Mir, Jeffrey Baldwin, James L. Van Etten, Nick V. Grishin, Anthony E. Pegg, Bruce A. Stanley and Margaret A. Phillips* Departments of Pharmacology and Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, Texas 753909041, Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey 17033, USA and Dept. of Plant Pathology and Nebraska Center for Virology, University of Nebraska, Lincoln, Nebraska 68583-0722 *Author to whom all correspondence should be addressed. Tel: (214) 648-3637 Fax: (214) 648-9961 e-mail: [email protected]
منابع مشابه
Paramecium bursaria chlorella virus-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylases.
Paramecium bursaria chlorella virus (PBCV-1) is a large double-stranded DNA virus that infects chlorella-like green algae. The virus encodes a homolog of eukaryotic ornithine decarboxylase (ODC) that was previously demonstrated to be capable of decarboxylating l-ornithine. However, the active site of this enzyme contains a key amino acid substitution (Glu for Asp) of a residue that interacts wi...
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